Asymmetric acylation of meso-diols with benzoyl halide in the presence of a chiral diamine

Abstract Nonenzymatic desymmetrization of cis -1,2-cyclohexanediol by the asymmetric acylation with achiral benzoyl chloride in the presence of a chiral diamine derived from (S) -proline took place to give monobenzoate in high optical yield.