СОВРЕМЕННЫЕ ПРЕДСТАВЛЕНИЯ О ПРИЧИНАХ И МЕХАНИЗМАХ ФОРМИРОВАНИЯ АПОПЛЕКСИИ ЯИЧНИКА. ОСОБЕННОСТИ ВЛИЯНИЯ КЛИМАТИЧЕСКИХ УСЛОВИЙ СУБАРКТИЧЕСКОГО РЕГИОНА НА РАЗВИТИЕ ПАТОЛОГИИ

The study aims to analyze the literature data on the causes and mechanisms of ovarian apoplexy and the development of recurrence of pathology in women, including those living in unfavorable climatic conditions of the subarctic region. Material and methods. A literature search is carried out in international and Russian databases such as MEDLINE, PubMed, CyberLeninka, eLIBRARY.RU, Scopus, and Web of Science. The search depth averaged out ten years. For the literary search, the following keywords are used: ovarian apoplexy, adaptation diseases, functional neuroendocrine disorders, menstrual disorder, metabolic syndrome, hemostasis, nonspecific protection. During the search, eighty articles are selected on the topic of research. Only forty of them, counting thirteen foreign ones, are included in this systematic review. Results. Despite the frequency of occurrence of this pathology, the scientific literature has not revealed convincing data on the causes and mechanisms of its formation, which would make it possible to offer personalized methods of treatment and prevention of recurrence of ovarian apoplexy in women living in unfavorable climatic conditions of the Middle Ob region. The need for further research in this direction is obvious.