Effects of salvianolate on bone metabolism in glucocorticoid-treated lupus-prone B6.MRL-Fas (lpr) /J mice.

Yanzhi Liu,Yang Cui,Xiao Zhang,Xiang Gao,Yanjie Su,Bilian Xu,Tie Wu,Wenshuang Chen,Liao Cui

Effects of salvianolate on bone metabolism in glucocorticoid-treated lupus-prone B6.MRL-Fas (lpr) /J mice.

2016

Yanzhi Liu
Yang Cui
Xiao Zhang
Xiang Gao
Yanjie Su
Bilian Xu
Tie Wu
Wenshuang Chen
Liao Cui

Aim To investigate the bone-protective effects of salvianolate (Sal), a total polyphenol from Radix Salviae miltiorrhizae, on bone tissue in the spontaneous lupus-prone mouse model, B6.MRL-Faslpr/J, undergoing glucocorticoid (GC) treatment.

Keywords:

Pharmacology
Bone remodeling
Glucocorticoid
Diabetes mellitus
Endocrinology
Systemic lupus erythematosus
X-ray microtomography
Bone tissue
Internal medicine
Medicine
Osteoporosis
Immunohistochemistry
Prednisone
Bone resorption

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