Usefulness of measurement of glucose and glycosylated hemoglobin levels in patients with acute coronary syndrome as predictors of number of stenotic coronary arteries as shown in coronary arteriography

UNLABELLED: Data on corelation between diabetes and multivessel coronary disease have been documented. The aim of the study was to estimate usefulness of measurement of glucose and glygosylated haemoglobin levels in patients with acute coronary syndrome as a predictors of number of stenotic coronary arteries shown in coronary arteriography. METHODS: We examined 386 patients (mean age was 61 +/- 10, men/ women 263/123). All of them underwent coronary angiography 81 patients (21%) had diabetes. A routine examination included age, sex, clinical state, BMI, WHR, plasma lipids, coagulative parameters, glucose level, HbA1c level, urea, creatine, C-reactive protein levels, blood pressure and heart failure traits. RESULTS: There were 11.2% patients without any changes in coronary arteries, 28.4% patients with one or two stenotic arteries and 60.4% patients with more than two stenotic coronary arteries. We observed that glucose and HbA1c levels were significantly higher in group without any changes vs group with one or two stenotic vessels and more than two stenotic vessels. The differences were still statistically significant in patients with diabetes and HbA1c over 6.2%. CONCLUSION: In conclusion, measurement of glucose and glycosylated haemoglobin levels in moment of diagnosis acute coronary syndrome can have prognostic estimation of number of stenotic arteries.