First Synthesis of 3,6′- and 3,7′-Biquinoline Derivatives

The preparation of new 3,6′- and 3,7′-biquinoline derivatives was achieved by microwave-assisted Suzuki cross-coupling between N-protected 6- or 7-bromoquinolin-2(1 H)-ones and quinolin-3-ylboronic acid. Moreover, a new synthesis of 7-bromoquinolin-2(1 H)-one leading solely to the 7-substituted isomer was carried out.