Cardiorespiratory Dysfunction Induced by Brainstem Spreading Depolarization: A Potential Mechanism for SUDEP.

Sudden unexpected death in epilepsy (SUDEP) is the main cause of death in people with refractory epilepsy ([Massey et al., 2014][1]; [Buchanan, 2019][2]), but the mechanisms responsible for SUDEP are still unclear. Evidence from animal and human studies suggests that SUDEP is related to an