Application of parallel-plate flow chamber in cancer research

Parallel-plate flow chamber is a widely used equipment in studying cellular mechanics in vitro. Many researchers used parallel-plate flow chamber to provide shear stress and to mimic in vivo the environment of cancer cell growth. It is a versatile tool in understanding the mechnisms of proliferation,adhesion,and metastasis of cancer cell. Cancer-detecting devices were also developed based on parallel-plate flow chamber. A new field overlapping biomechanics and cancer research was developed. Application of parallel-plate flow chamber in cancer research is reviewed in this paper.