Left ventricle partial and global diastolic function evaluated in patients with silent myocardial ischemia by Doppler combined with dobutamine stress echocardiography

Objective To evaluate left ventricle partial and global diastolic function in patients with silent myocardial ischemia (SMI) by Doppler tissue imaging (DTI) combined with dobutamine stress echocardiography (DSE).Methods 30 cases of silent myocardial ischemia(SMI) and 30 cases of normal control underwent dobu-tamine stress echocardiography(DSE). DTI was acquired at baseline and stress, and waveforms in mitral valve clos- ing, and the base and mid segments of left ventricle were used to measure diastolic early velocity(Ve), diastolic lately velocity(Va) ,and E deceleration time(Te). Results Ⅴ in control group increased accompanied with the increasing dose of dobutamine, Ve/Va decreased a little but not significantly. Ⅴ in the group with silent myocardial ischemia (SMI) increased at 10μg·kg-1·min-1 ,but decreased at 40μg·kg-1·min-1 compared with 10μg·kg-1·min-1 ,T in both control and DSE group decreased at 40μg/kg accompanied with 10μg·kg-1·min-1, T in both control and DSE group decreased accompanied with the increasing dose of dobutamine, and there were significant differences between the groups(P < 0.05). Conclusion DTI-DSE could quantificadvely detect the partial and global diastolic function of left ventricle. Key words: Ultrasonography, Doppler, color;  Echocardiography;  Myocardial ischemia;  Heart function tests