Abstract MP34: Collecting Duct Cells-derived Human Sprr Impairs The Antihypertensive Effects Of Losartan And Upregulates Erk1/2 And Aqp2 Expression

Gertrude Arthur,Audrey Poupeau,Kellea Nichols,Jacqueline R Leachman,Analia S. Loria,Jeffrey L. Osborn,Frederique Yiannikouris

Abstract MP34: Collecting Duct Cells-derived Human Sprr Impairs The Antihypertensive Effects Of Losartan And Upregulates Erk1/2 And Aqp2 Expression

2021

Gertrude Arthur
Audrey Poupeau
Kellea Nichols
Jacqueline R Leachman
Analia S. Loria
Jeffrey L. Osborn
Frederique Yiannikouris

Recent studies showed that soluble prorenin receptor (sPRR) plays an important role in blood pressure regulation and in water balance. In rodent models, sPRR contributes to AngII production by incr...

Keywords:

Aquaporin 2
Cancer research
Losartan
Medicine
duct

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