[Corneal neurotrophic ulcers--clinical and etiopathogenic aspects].

PURPOSE: The aim of this paper is to observe the corneal neurotrophic ulcers in patients with ophthalmic and systemic diseases associated with impairment of the sensory innervation of the cornea. METHODS: We have performed a retrospective study using a lot of patients with corneal neurotrophic ulcers, admitted in Ophthalmology Clinic in 2003-2006. We have analyzed the etiopathogenic factors that have determined the corneal trophic ulcers, the treatment and the complications occurred. RESULTS: The study spot-lighted two main causes responsible for the corneal trophic ulcers: ocular and systemic disorders. For many patients the etiopathogenic factor is multiple. CONCLUSIONS: 1. Corneal neurotrophic ulcer is a severe complication of an ophthalmic or a systemic disorder. 2. The moderate outcome of ophthalmic complications require early treatment, adjusted for each patient. 3. Prevention of the corneal neurotrophic ulcers is the best method of treatment.