Thymoquinone treatment modulates the Nrf2/HO-1 signaling pathway and abrogates the inflammatory response in an animal model of lung fibrosis

Ajaz Ahmad,Khalid M. Alkharfy,Basit L. Jan,Abdul Ahad,Mushtaq A. Ansari,Fahad I. Al-Jenoobi,Mohammad Raish

Thymoquinone treatment modulates the Nrf2/HO-1 signaling pathway and abrogates the inflammatory response in an animal model of lung fibrosis

2020

Ajaz Ahmad
Khalid M. Alkharfy
Basit L. Jan
Abdul Ahad
Mushtaq A. Ansari
Fahad I. Al-Jenoobi
Mohammad Raish

AbstractThe present study investigates the therapeutic potential of thymoquinone (TQ) in bleomycin-induced lung fibrosis (BMILF) and elucidates the target-signaling pathway for its effect. Lung fib...

Keywords:

Thymoquinone
Lung
Lung fibrosis
Signal transduction
Cancer research
Animal model
Biochemistry
Inflammation
Oxidative stress
Bleomycin
Biology
inflammatory response

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