New method for clinical detection of cancer by rapidly analyzing the argon-laser-induced autofluorescence spectra

The paper presents a new method for malignant tumor diagnosis by rapidly detecting the argon laser induced autofluorescence spectra. The diagnostic system consists of an argon laser and an optical multichannel analyzer. With a special processing program, the spectral signal acquisition and the specific index I s /I analyzing could be done simultaneously in real time by a micro-computer. The system can not only be used for spectral measurement of separate points individually, but applied to continuous I s I scanning of entire suspicious areas as well. By this technique, the Lewis lung tumors less than 1 mm were identified in in-vivo experiments, and the human cancer of 2 mm was found in clinical detections.