Thymosin β4 is an Endogenous Iron Chelator and Molecular Switcher of Ferroptosis

Joanna Izabela Lachowicz,Giusi Pichiri,Marco Piludu,Sara Fais,Germano Orrù,Terenzio Congiu,Monica Piras,Gavino Faa,D. Fanni,Gabriele Dalla Torre,Xabier Lopez,Kousik Chandra,Kacper Szczepski,Łukasz Jaremko,Mitra Ghosh,Abdul-Hamid M. Emwas,Castagnola Massimo,Mariusz Jaremko,Ewald Hannappel,Pierpaolo Coni

Thymosin β4 is an Endogenous Iron Chelator and Molecular Switcher of Ferroptosis

2021

Financial support from FIR 2019 and from Regione Autonoma della Sardegna (grant RASSR79857) is gratefully acknowledged. We acknowledge the CeSAR (Centro Servizi d'Ateneo per la Ricerca) of the University of Cagliari, Italy for the Transmission Electron microscopic analysis performed with the JEOL 1400 plus TEM.

Keywords:

macrophage cell
electron microscopic
Cell biology
Neurodegeneration
Endogeny
thymosin β4
Iron Chelator
Ferroptosis
Chemistry

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