Influencing factors for operation timing and prognosis in patients with intracranial aneurysms

Objective To study the relationship between operation timing and the prognosis of patients with intracranial aneurysms. Methods In this study, we retrospected and followed up 654 cases of intracranial aneurysm undergoing microsurgical treatment. These patients were divided into groups by the operation timing and the complication of infarction after surgery. All data were analyzed by χ2 test. Results Among 654 cases in this study, 538 (82.26%) got eusemia, of which 231 (80.20%) in early surgery group, 54 (66.67%) in intermediate surgery group and 253 (88.77%) in late surgery group. Among 415 (63.46%) cases of follow-up, 342 (82.41%) got eusemia, of which 153 (79.69%) in early surgery group, 27 (61.36%) in intermediate surgery group and 162 (90.50%) in late surgery group. Among 654 cases of surgery, 135 (20.64%) got new cerebral infarction after surgery, of which 68 (23.61%) in early surgery group, 22 (27.16%) in intermediate surgery group and 45 (15.79%) in late surgery group. Conclusion Operation timing is one of the most important infludencing factors in intracranial aneurysms treatment. The outcome of late surgery is better than early surgery, while the prognosis of intermediate surgery is inferior to early surgery. Patients given late surgery will be confronted with greater risk of aneurysm rupture during the waiting for surgery. Therefore, the early surgery is recommended, while the intermediate surgery is not recommended, unless the patients have massive intracranial hematoma or hernia. Key words: Intracranial aneurysm; Operation time; Prognosis