Circulation studies in experimental phlegmasia cerulea dolens.

Abstract A model of phlegmasia cerulea dolens in the canine hind limb was used to study the effects of heparin, sympathectomy, and venous thrombectomy plus heparin on limb hemodynamics. Only thrombectomy plus heparin restored nutrient blood flow and was associated with clinical recovery of the limb. This experimental model of phlegmasia appears to be an excellent tool for testing additional modalities of therapy for this serious disease.