Therapeutic Effect of Bivalirudin in AMI Patients Undergoing Emergency PCI

Objective To evaluate the 30-day efficacy of bivalirudin in patients with acute myocardial infarction(AMI) who underwent emergency PCI.Methods Fifty-eight AMI patients admitted from February to July 2012 had symptoms and received emergency PCI,thereinto 30 patients had bivalirudin before PCI,28 had unfractioned heparin(UFH).Results No significant difference was noted in interventional treatment path,TIMI blood flow,number of diseased vessels between 2 groups(P0.05),but there was in utilization ratio of manual thrombus suction device and tirofiban(P0.05).No deaths,stent thrombosis or recurrent myocardial infarction occurred during 30-day follow-up.There was not difference in re-hospitalization rate,incidence of heart failure or other adverse reaction between 2 groups(P0.05).In UFH group 1 had severe bleeding,but in bivalirudin group no one had.Conclusion Using bivalirudin in emergency PCI is of good safety in AMI patients.