Phosphonosulfonate squalene synthetase inhibitor

PROBLEM TO BE SOLVED: To obtain a new phoshonosulfonate salt inhibiting cholesterol biosynthesis and useful for treating hyperlipidemia, hyperlipoproteinemia, hypercholesterolemia, atheroscierosis, etc. SOLUTION: A compound of formula I (X is t-butylamine salt, t-octylamine salt, dehydroabietylamine salt). For example, a compound of formula II. The compound of formula I is obtained e.g. by treating a calcium salt of formula III with an ion exchange resin and subsequently reacting the obtained free acid with an amine reactant. COPYRIGHT: (C)1996,JPO