Trial with Idiopathic Short Stature: A Randomized, Double-Blind, Placebo-Controlled Effect of Growth Hormone Treatment on Adult Height in Peripubertal Children

Developmental Endocrinology Branch (E.W.L., J.A.Y., J.B.) and Biometry and Mathematical Statistics Branch (J.F.T.),National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892;Department of Endocrinology (S.R.R.), Children’s Hospital Medical Center, Cincinnati, Ohio 45229; Eli Lilly and Company(C.A.Q., J.J.C., B.J.C., W.F.B., G.B.C.), Indianapolis, Indiana 46285; Department of Pediatrics (J.L.R.), Thomas JeffersonUniversity, Philadelphia, Pennsylvania 19107; Alfred I. duPont Hospital for Children (J.L.R.), Wilmington, Delaware19899; and Institute of Maternal and Child Research (F.G.C.), University of Chile, Santiago, Chile