Multiple heart valve involvement in renal polycystic disease in the adult

: Adult polycystic kidney disease is associated with frequent extrarenal manifestations. Previous studies have reported a increased incidence of cardiovascular abnormalities, in particular of mitral and tricuspid-valve prolapse, and multivalvular incompetence. These findings lends support to the hypothesis that autosomal dominant polycystic kidney disease is a disorder of connective tissue. A mitral-valve prolapse, and multivalvular incompetence was detected in a 75-year old patient with a polycystic kidney disease. The cardiovascular abnormalities published in the literature are review.