Synthesis of Chromene Derivatives via Three‐Component Reaction of 4‐hydroxycumarin Catalyzed by Magnetic Fe3O4 Nanoparticles in Water

An easy and effective procedure for one-pot three components coupling of 4-hydroxycumarin, isothiocyanates, and isocyanides in water by employing magnetically recoverable Fe3O4 nanoparticles is described. Variety of chromene were produced a derivatives in high yields by using of this procedure. The catalyst can be recovered and recycled without a considerable decrease in the catalytic activity.