Acute Kidney Recovery in Patients Undergoing Transcatheter Versus Surgical Aortic Valve Replacement (From the Northern New England Cardiovascular Disease Study Group)

Abstract Acute kidney recovery (AKR) is a recently described phenomenon observed after transcatheter aortic valve replacement (TAVR) and is more frequent than acute kidney injury (AKI). To determine the incidence and predictors of AKR between surgical aortic valve replacement (SAVR) and TAVR. We examined patients with chronic kidney disease and severe aortic stenosis undergoing SAVR or TAVR procedure between 2007-2017; excluding age 90, dialysis, endocarditis, non-aortic valve stenosis, or patients died within 48-hours post-procedure. AKR was defined as an increase of estimated glomerular filtration rate (eGFR) > 25% and AKI as decrease in eGFR > 25% at discharge. Stroke, mortality, major bleeding, transfusion, and length of stay were examined. Multivariate logistic regression analysis was used to examine predictors of AKR. There were 750 transcatheter and 1,062 surgical patients and 319 pairs after propensity matching. AKR was observed in 26% TAVR vs 23.2% SAVR, p=0.062. Highest recovery was in patients with eGFR