Synthèse d'analogues de dérivés dioxaprostanoïques à partir du d et du l-xylose

Abstract Epoxides 7 , 8 and 9 have been prepared from d and l -xylose, and used for the synthesis of a precursor of ent -(11-oxa)PG 19 and of 9,13-and 7,11-dioxaprostanoic acids 28 and 31 . The site of the opening of the epoxidcs 7 and 9 with the carbanion derived from bis -(phenylth)romethane and with LiAlH 4 is shown by establishing structures of the products 11 , 12 , 20 et 21 by 13 CNMR spectroscopy.