[Ionic mechanisms of the electrical activity of the smooth-muscle cells of the lymphatic vessels].

: APs of smooth muscles of isolated lymphatic vessels were recorded by means of the single sucrose-gap method. Plateau APs with sharp spikes on the plateau were recorded in Krebs' solution. Low-sodium solutions led to discontinuation of the plateau phase whereas calcium-free solution eliminated the sharp spikes. Increase of the intravascular pressure during the action of D-600 blocking agent activated the electrical activity which suggests that smooth muscle cells have channels of mechanical sensitivity. Intracellular Ca2+ seems to participate in the contractile mechanism.