SYNTHESIS AND PROPERTIES OF SUBSTITUTED 1-(2-BENZOTHIAZOLYL)-2-PYRIDONES

The studied 1-(2-benzothiazolyl)-2-pyridones Va-Vf were prepared from N -(2-benzothiazolyl)cyanoacetamide (II) which on reaction with 4-substituted benzaldehydes afforded 3-aryl- N -(2-benzothiazolyl)-2-cyano-2-propenamides IVa-IVg . Compounds IVa-IVf were cyclized with malonodinitrile in the presence of piperidine to give the corresponding pyridones Va-Vf .