TRPML1 Participates in the Progression of Alzheimer’s Disease by Regulating the PPARγ/AMPK/Mtor Signalling Pathway

Lu Zhang,Yu Fang,Xuan Cheng,Yajun Lian,Hongliang Xu,Zhaoshu Zeng,Hongcan Zhu

TRPML1 Participates in the Progression of Alzheimer’s Disease by Regulating the PPARγ/AMPK/Mtor Signalling Pathway

2017

Lu Zhang
Yu Fang
Xuan Cheng
Yajun Lian
Hongliang Xu
Zhaoshu Zeng
Hongcan Zhu

Background: TRPML1 is reported to be involved in the pathogenesis of Alzheimer’s disease (AD) by regulating autophagy; however, the underlying mechanism is not co

Keywords:

Biochemistry
Hedgehog signaling pathway
PI3K/AKT/mTOR pathway
Autophagy
Cancer research
RPTOR
Disease
AMPK
Pathogenesis
Biology
P70-S6 Kinase 1
Activator (genetics)
Viability assay
Lysosome
Cell biology

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