Metabolic outcomes in young children with type 1 diabetes differ between treatment centers: the Hvidoere Study in Young Children 2009

Objective: To investigate whether center differences in glycemic control are present in prepubertal children Research Design and Methods: This cross-sectional study involved 18 pediatric centers worldwide. All children, Results: A total of 1133 children participated (mean age: 8.0 +/- 2.1 y; females: 47.5%, mean diabetes duration: 3.8 +/- 2.1 y). HbA1c (overall mean: 8.0 +/- 1.0%; range: 7.3-8.9%) and severe hypoglycemia frequency (mean 21.7 events per 100 patient-years), but not DKA, differed significantly between centers (p Conclusions: Center differences in metabolic outcomes are present in children