Fxa inhibitors with cyclic amidoxime or cyclic amidrazone as p4 subunit, processes for their preparations, and pharmaceutical compositions and derivatives thereof

2008 
The present invention relates to an invention relating to oxazolidinone derivatives or pharmaceutically acceptable salts thereof, their preparation and pharmaceutical compositions containing them having an novel cyclic amino doksim or cyclic amidrazone of formula I . [Formula I] [In Formula I, A ring is selected from the following structure; Cyclic amino doksim or cyclic in accordance with the present invention amidrazone acceptable salt of the oxazolidinone derivatives and their pharmaceutically having a group is useful in the treatment of thromboembolism and tumor agent wherein through the inhibition of coagulation factor Xa clot It can be. Cyclic amino doksim, cyclic amidrazone, oxazolidinone, factor Xa, anticoagulant
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