Effect of postpartum prostaglandin tromethamine on postpartum hemorrhage

Objective To investigate the effect of using carprostol tromethamine when postpartum vaginal bleeding reaches 300 ml and 500 ml on postpartum hemorrhage. Methods select 180 women with a bleeding volume more than 300 ml during transvaginal delivery after hospitalization at our hospital from October, 2015 to October, 2017 were selected as study objects, and were randomly divided them into an intervention group (n=90, treated with prostaglandin tromethamine when the bleeding volume reached 300 ml) and a control group (n=90, tereated with prostaglandin tromethamine when the bleeding volume reached 500 ml). The bleeding volumes 2 and 24 h after delivery and the incidences of postpartum hemorrhage and blood transfusion were compared between the two groups. Results The bleeding volumes 2 and 24 h after delivery were higher in the intervention group than in the control group (both P<0.05). The incidences of postpartum hemorrhage and blood transfusion were lower in the intervention group than in the control group (8.89% vs. 21.11% and 4.44% vs. 16.67%, both P<0.05). Conclusions Early treatment with carprostol tromethamine for patients with large postpartum hemorrhage can reduce the total bleeding volume and reduce the incidences of postpartum hemorrhage and blood transfusion. Key words: Postpartum hemorrhage; Oxytocin; Carprostol tromethamine