Methods and apparatus for the detection of tau protein deposits in the eye

There are provided methods and devices for the detection of paired helical τ filaments τ PHF in the eye (100) in which, for example, by means of a camera device (103), an overview image is created with a laser scanner device on the basis of the overview image identified regions of interest to be scanned, in order to fluorescence of paired helical filaments bonded τ (107) probes (108) to be detected.