Focal adhesion kinase (FAK) inhibitors VS-6063 and VS-4718 target cancer stem cells.

Qunli Xu,Vihren N. Kolev,Quentin G. Wright,Irina M. Shapiro,Christian M. Vidal,Mahesh Padval,Mitchell Keegan,Daniel Paterson,Joanna Horobin,Jonathan A. Pachter

Focal adhesion kinase (FAK) inhibitors VS-6063 and VS-4718 target cancer stem cells.

2017

Qunli Xu
Vihren N. Kolev
Quentin G. Wright
Irina M. Shapiro
Christian M. Vidal
Mahesh Padval
Mitchell Keegan
Daniel Paterson
Joanna Horobin
Jonathan A. Pachter

e13523 Background: Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that orchestrates cellular signaling through integrins and growth factor receptors and functions in multiple steps o...

Keywords:

Growth factor receptor
Integrin
Pathology
Cancer stem cell
Cancer research
Focal adhesion
Tyrosine kinase
Cell signaling
Medicine

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