Evaluation of c337g polymorphism of fshr gene in the population of black0and-white holsteinized cattle

One of the crucial step of the technology of accelerated reproduction of cattle is selection of donor cows, which are the most sensitive to the procedure of hormonal stimulation of ovulation. To date, one of the promising genetic markers of the reproductive status of cattle is the follicle-stimulating hormone receptor (FSHR) gene. Special attention is drawn to SNP C337G (rs43745234), associated with the number of fertilized oocytes and viable embryos. The aim of this work was to evaluate the polymorphism C337G of the FSHR gene in a population of Black-and-White holsteinized cattle. The article presents data on genotyping of 190 Black-and-White holsteinized cows by the allelic variants C337G of FSHR gene (rs43745234) by PCR-RFLP method. Analysis of the results showed that in the studied cattle population C and G allele frequencies were 0,7 and 0,3. The frequencies of genotypes C/C and C/G  were 474 and 0,453, respectively. The frequencies of G/G genotype associated with a large number of viable embryos (according to literature data) was only 0,074.