Efficacy andsafety oftransarterialchemoembolization combined toconformal radiotherapy foruninodularhepatocellular carcinoma

-scan or MRI at month-1 and-3, and thereafter evermonths.Results:Complete response wasobtained in 80% of patients following mR ECIST criteria (95% in HCC"d50 mm, and 60% in HCC > 50 mm) with uncommon local recurrence (11%), overall survival rates of 79%, 59% and 44% at respectively 1, 2 and 3 years (median, 37.3 months ), and 11.4% grade -3/4toxicities. Pre -therapeutic �± -fetoprotein level "e 200 ng/mL was found as a strong predictor of poorer outcome. Conclusion:We showed that TACE combined to 3D-HDCRT can be highly efficient to reach local control and interesting overall survival rates for u ninodular HCC, with limited severe toxici ties for Child -Pugh A patients.Subsequent prospective controlled trials are warranted for compari son with therapeutic standards .