Risk Factors and Outcome Analysis in Children with Carbon Monoxide Poisoning

Background Carbon monoxide (CO) poisoning is one of the common causes of poisoning in patients and can result in significant morbidity and mortality. However, few studies have focused on the pediatric group. Methods We retrospectively reviewed children (age  Results A total of 81 children were enrolled. The annual case number increased from five cases in 2002 to 20 in 2010, particularly during the cold months (December to February). The most common source of exposure was an indoor heating system (54.3%). The most common presenting symptoms were vomiting (32.1%) and consciousness changes (30.9%). HBO treatment tended to be administered to patients with a higher initial COHb (%) ( p p p  = 0.002). After multivariate analysis, treatment in the intensive care unit because of prolonged loss of consciousness ( p  = 0.002) was the only independent risk factor for patients with DNS; only rescue by a ventilator ( p Conclusion For those with treatment in the intensive care unit because of prolonged loss of consciousness and rescue by a ventilator, special attention should be given and follow-up should be performed to determine whether DNS or PNS occurs, particularly epilepsy and cognitive deficits.