Modeling of an Actif Cyclic Electromagnetic Effect on Hemozoin for Malaria Diagnosis Computerized Electromagnetic Effect on Hemozoin for Malaria Diagnosis
2018
In this work we present the heat generated by the super magnetic particle, the waste prevent from the plasmodium degradation. The hemozoin behaviour due to electromagnetic field applied on it will be used as a sensitive method for malaria diagnosis. Hemozoin presents its self in the form of a crystal and which constitutes a pigment synthesised by the malaria parasite with the aim of annihilating the toxic effect ofhematine. In effect, after contamination the plasmodium dwells inside the red blood cells of the host so as to feed itself with the amino-acids obtained by degradation of hemoglobin. But during this “meal” the parasite liberates a waste product in the form of a complex made of porphyrin and iron. In order to prevent that noxious effect, the plasmodium polymerizes the complexes of porphyrin inside a digestive vacuole to finally produce a crystal of a hemozoin not toxic for him. This particle is previously paramagnetic because of the presence of iron in the red blood cells. This paper proposes the modeling of magnetic field effect of hemozoin for malaria detection. The potential effect of the cyclically activated magnetic field was modeled using a thermodynamic framework. Then at the end, generation and diffusion of heat due to the presence of constant cyclically magnetic field have been determined. These to prove how the pull or push forces between the particles of Hemozoin are demonstrated by producing the heat. The energy inside the particle is also taken into consideration in the cell while doing the diagnosis of malaria.
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