Trends in U.S. emergency department visits for anaphylaxis among infants and toddlers: 2006-2015.

ABSTRACT Background Anaphylaxis is a potentially life-threatening allergic reaction. The overall prevalence of anaphylaxis appears to be rising in children, but temporal trends among infants and toddlers are not well studied. Objective To characterize the trends in U.S. emergency department (ED) visits and hospitalizations among infants and toddlers with anaphylaxis from 2006-2015. Methods We conducted a study of temporal trends in anaphylaxis among children (age Results Among infants and toddlers, the proportion of ED visits for anaphylaxis per year increased from 20 per 100,000 visits to 50 per 100,000 visits (Ptrend Conclusion In a large, nationally representative US database, from 2006 to 2015, ED visits by infants and toddlers with anaphylaxis increased, while hospitalization of these patients decreased.