Strain Analysis Using Feature-Tracking CMR to Detect LV Systolic Dysfunction in Myocardial Iron Overload Disease

Iron-induced cardiomyopathy with progressive heart failure is the leading cause of death in patients with systemic iron overload, and early detection is vital for chelator therapy ([1][1]). The transverse relaxation time T2∗ (=1/R2∗) nonlinearly reflects tissue iron concentration and allows pre-