Rare combination of familial adenomatous polyposis and gallbladder polyps

Familial adenomatous polyposis is associated with a high incidence of malignancies in the upper gastrointestinal tract(particularly ampullary adenocarcinomas).However,few reports have described a correlation between familial adenomatous polyposis and gallbladder neoplasms.We present a case of a 60-year-old woman with familial adenomatous polyposis who presented with an elevated mass in the neck of the gallbladder(measuring 16 mm×8 mm in diameter)and multiple small cholecystic polyps.She had undergone a total colectomy for ascending colon cancer associated with familial adenomatous polyposis 22 years previously.The patient underwent laparoscopic cholecystectomyunder a preoperative diagnosis of multifocal gallbladder polyps.Pathologic examination of the resected gallbladder revealed more than 70 adenomatous lesions,a feature consistent with adenoma of the gallbladder.This case suggests a requirement for long-term surveillance of the biliary system in addition to the gastrointestinal tract in patients with familial adenomatous polyposis.