Attenuation of Space Radiation-Induced Damage by an Oral Supplementation with a Mixture of Micronutrients in Astronauts
2021
Context: There are no effective radiation protection strategies to protect the
astronauts against space radiation while traveling beyond the earth-orbit.
Objectives: The objectives are to characterize space radiation and its ability to
produce reactive oxygen species and inflammation that can increase adverse
health effects in astronauts. Because of limitation of using a single or a mixture
of few antioxidants, it proposes a comprehensive mixture of micronutrients for
prevention and mitigation of radiation damage in astronauts.
Methods: Critical analysis of the published studies on space radiation-induced
adverse health effects on astronauts and their countermeasures obtained from
the PubMed Central was performed.
Results: While traveling beyond the earth-orbit, astronauts are exposed to galactic
cosmic rays (GCRs), solar particles events, and (c) electrons and protons trapped
in the Van Allen Belts. Space radiation enhances oxidative stress and inflammation
that are associated with increased health risks. Administration of a single or
a mixture of few antioxidants may not be adequate for radiation protection
astronauts. Therefore, a comprehensive mixture of micronutrients for prevention
and mitigation of space radiation injury is proposed.
Conclusion: Astronauts travelling beyond the earth orbit are exposed to space
radiation, which enhance oxidative stress and inflammation that can produce
adverse health effects. A comprehensive micronutrient mixture may prevent
and mitigate adverse health effects in astronauts by simultaneously reducing the
above cellular deficits.
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