188Re-HEDP for palliation of pain from bone metastases

188Re-HEDP is a bisphosphonate which preferentially incorporates into the sites of bone metastases.It interacts with bone metabolism,suppresses the activity of osteolysis,and gathers in tumor bone metastases.Recently,researches show that 188Re-HEDP has some advantages for palliation of bone metastasisrelated pain because of its favorable physicochemical and biological characteristics,188Re-HEDP radioisotopes therapy will be an effective method for bone metastatic tumors. Key words: Rhenium;  Radiotherapy;  Neoplasm metastasis;  Bone neoplasms