Dynamics Of Cell Components Investigated With Nanovid Microscopy

A new technique for the visualization of small molecular components in living cells is presented. It is based on the exploitation, by means of video techniques of the slight diffraction power of small metal particles (20-40 nm) in the light microscope. We will show that colloidal gold probes, coupled to selective antibodies or charge modulating molecules allow to follow and quantify dynamic processes in endocytosis, Saltatory Motion and membrane mobility.