Plasma concentrations and pharmacokinetics of idebenone and its metabolites following single and repeated doses in young patients with mitochondrial encephalomyopathy.

Pascale Pisano,Alain Durand,E. Autret,C. Desnuelle,N. Pinsard,G. Serratrice,V. Legout,M. Joubert,Olivier Blin

Plasma concentrations and pharmacokinetics of idebenone and its metabolites following single and repeated doses in young patients with mitochondrial encephalomyopathy.

1996

Pascale Pisano
Alain Durand
E. Autret
C. Desnuelle
N. Pinsard
G. Serratrice
V. Legout
M. Joubert
Olivier Blin

Objective: The pharmacokinetics and tolerance of idebenone after single or repeated doses have been studied in young patients with mitochondrial encephalomyopathy.

Keywords:

Idebenone
Mitochondrial encephalomyopathy
Mitochondrial Encephalomyopathies
Oral administration
Mitochondrial myopathy
Medicine
Toxicity
Phenobarbital
Pharmacokinetics
Internal medicine
Endocrinology

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