Linfomas en el mesenterio: características clinicopatológicas en 30 pacientes venezolanos

Background: Mesenteric lymphomas is a rare entity, most are secondary to primary gastrointestinal, ovarian or retroperitoneal tumors. Objective: To know frequency and histopathologic varieties of lymphomas affecting mesenteric, as well as the importance of the immunophenotypic studies for their identifi cation and distinction with the different benign and malignant injuries simulating them. Material and methods: We reviewed 30 fi les from Limphohematopoiectic Pathology section, Anatomopathological Institute, Medicine School, Venezuela Central University, across 15 years. Clinical information was obtained from the requests that accompanied to the biopsies or surgical supplies acquired by laparotomy (29 cases) and fi ne needle (1 case). Results: We registered 28 non-Hodgkin’s and 2 Hodgkin’s lymphomas (16 males and 14 females with ages from 18 months to 75 years). In 12 patients, non-Hodgkin’s lymphomas were diffuse large cell; 12 Burkitt’s type diffuse; 3 small cleaved follicular center cell or centrocytic (2 diffuse and 1 follicular grade 1), and one case with diffuse lymphoplasmocytoid lymphoma. The two Hodgkin’s lymphomas were nodular sclerosing. Conclusions: The mesenteric lymphomas belonged, mainly, to lymphomas non-Hodgkin diffuse of great cells and lymphocytes B in adult patients, and of Burkitt type in children. Their differentiation with other benign and malignant processes, primary and secondary, requires the histological and immunophenotypic study.