New triterpene and nor-diterpene derivatives from the leaves of Adinandra poilanei

Abstract Two new compounds, adinandrolide (1) and adipoiloside (2), together with twelve known compounds 3–14, were isolated and identified from Adinandra poilanei leaves. In the α-glucosidase activity evaluation, compounds 5–7 and 10 strongly inhibited enzyme activity with IC50 values ranging from 1.29 ± 0.03 μg/mL to 3.13 ± 0.07 μg/mL. Compounds 9, 11, and 13–14 showed significant inhibition with IC50 values of 13.01 ± 0.32 μg/mL to 16.00 ± 0.35 μg/mL, while adipoiloside (2) displayed moderate inhibitory activity. In addition, pomolic acid (10) showed strong cytotoxicity against four tested cancer cell lines.