The effect of stellate ganglion block with ropivacaine on inflammatory reaction in patients undergoing cardiopulmonary bypass

Objective To study the effect of stellate ganglion block with ropivacaine on inflammatory reaction in patients undergoing cardiopulmonary bypass.Methods Twenty patients undergoing mitral valve replacement were randomLy allocated to two groups,control group and SGB group(n=10).The control group was not treated.The SGB group was stellate blocked with 0.5% ropivacaine.The samples were taken at twenty minutes before the anesthesia(T1),twenty minutes after the anesthesia(T2),twenty minutes after the surgery(T3),twenty minutes during CPB(T4) and twenty minutes afterCPB(T5).Results IL-1βof the control group is higher than the SGB group at T5(P0.05).BG、Cor、IL-6、TNF-α of the control group are lower than the control group at T4 and T5.Conclusion Stellate ganglion block with ropivacaine can relieve inflammatory reaction induced by CPB.The mechanism need explore in the future.