Hailey–Hailey disease is caused by mutations in ATP2C1 encoding a novel Ca2+ pump
2000
Hailey–Hailey disease (HHD) is an autosomal dominant skin disorder characterized by suprabasal cell separation (acantholysis) of the epidermis. Previous genetic linkage studies localized the gene to a 5 cM interval on human chromosome 3q21. After reducing the disease critical region to
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