Method for detecting ibrutinib enantiomers

2017 
The invention discloses a method for detecting ibrutinib enantiomers, and belongs to the technical field of drug analysis. The method mainly comprises the following steps: preparing a system suitability test solution, preparing an enantiomer reference substance solution, preparing a sample solution, carrying out chromatographic conditions and system suitability test, and detecting the ibrutinib enantiomers. The detection method has the advantages of high accuracy, high precision and high durability, can accurately reflect the enantiomer content of an ibrutinib raw medicine, and is suitable for the industrial inspection and quality control of the ibrutinib enantiomers, so a reasonable basis is provided for the making of quality standards to well control and know the product quality, and the safety of clinical medication is increased.
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