Przedstawienie przypadków zapalenia wątroby wywołanego wirusem EBV

Epstein-Barr virus (EBV) belongs to the Herpesviridae family and is widely distributed in the world. It is transmitted through close contacts, and the source of infection is saliva. The source of infection could be also blood, blood derivatives and transplanted organs. EBV causes infectious mononucleosis and in rare cases hepatitis. The present article describes two cases of hepatitis in the course of infectious mononucleosis. The first patient, 26 years old, without chronic diseases was admitted to the hospital because of acute hepatitis features, in the course of hospitalization the patient developed typical symptoms of infectious mononucleosis. The second patient, 20 years old, initially had fever up to 40 degrees Celsius, during hospitalization the patient experienced typical symptoms of infectious mononucleosis and features of hepatitis. After treatment both patients were discharged in a good general condition, in symptoms remission phase. In the diagnosis of infectious mononucleosis caused by EBV we measure presence of specific antibodies against this virus: anti-VCA IgM. For both patients serological diagnostics was conducted and enabled the diagnosis of acute EBV infection. When doing differential diagnosis of hepatitis causes we should be aware of EBV infection possibility. Measurement of EBV specific antibodies plays an important role in confirming the disease.