Comparison of oral Midazolam with Ketamine versus oral Midazolam as a premedication in children

In paediatric patients midazolam and ketamine are commonly used as premedicants. This prospective randomized study was conducted to compare the efficacy of oral midazolam versus combination of midazolam and ketamine as premedicants in paediatric age group in 60 childrens. 30 in each group, aged 2–6 years, undergoing major and intermediate surgery were included in the study. Forty five (45) minutes prior to surgery group A received oral midazolam (0.5mg/kg) and group B received oral midazolam 0.25mg/kg and oral ketamine (3mg/kg) in recovery room.