[Alternate-day oral tadalafil for erectile dysfunction with no successful intercourse at the baseline].

Objective: To summarize the experience in the treatment of erectile dysfunction(ED) with no successful intercourse at the baseline with tadalafil.Methods: We retrospectively analyzed 21 cases of ED with no successful intercourse at the baseline treated with tadalafil on alternate days combined with sex guidance.Results: After 4 weeks of tadalafil treatment,19 of the patients achieved successful sexual intercourse,and the IIEF-5 score was remarkably improved as compared with pre-medication(3.24±1.55 vs 18.95±3.02,P0.0001).Mild adverse reactions were observed in 6 cases,including 2 cases of mild headache and 4 cases of facial blush.Conclusion: Tadalafil on alternate days combined with sex guidance can significantly improve ED with no successful intercourse at the baseline.