Динамика формирования изменений в центральной нервной системе при воздействии шума в эксперименте

The article presents the results of experimental studies on the effects of noise on the body of white rats. That long-term exposure to noise (1, 4 months) leads to an increase in slow-wave activity, as well as changes in visual and auditory cortical response, with an increase in latency and a decrease in the amplitude values of the main peaks, indicating that the stress response of animals to the stimulus. Additionally, chronic exposure leads to noise reduction in general motor activity, increased anxiety, reduced emotional activity animals. Pathological examination revealed a violation of the vascular nature when exposed to noise for 15 days, longer duration of action of factor causes irreversible changes in the nervous tissue in the form of reduction in the total number of neurons per unit area, the presence of glial scarring in the area of 2 layers of the cerebral cortex, increasing the number of cells astroglia.